Reovirus Variants Selected for Resistance to Ammonium Chloride Have Mutations in Viral Outer-Capsid Protein σ3

Mammalian reoviruses are internalized into cells by receptor-mediated endocytosis. Within the endocytic compartment, the viral outer capsid undergoes acid-dependent proteolysis resulting in removal of the σ3 protein and proteolytic cleavage of the μ1/μ1C protein. Ammonium chloride (AC) is a weak bas...

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Détails bibliographiques
Auteurs principaux: Clark, Kimberly M., Wetzel, J. Denise, Gu, Yingqi, Ebert, Daniel H., McAbee, Stephanie A., Stoneman, Emily K., Baer, Geoffrey S., Zhu, Yuwei, Wilson, Gregory J., Prasad, B. V. V., Dermody, Terence S.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2006
Sujets:
Virus-Cell Interactions
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1346852/
https://ncbi.nlm.nih.gov/pubmed/16378970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.2.671-681.2006
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