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Distinct Antifungal Mechanisms: β-Defensins Require Candida albicans Ssa1 Protein, while Trk1p Mediates Activity of Cysteine-Free Cationic Peptides

Salivary histatin 5 (Hst 5) kills the fungal pathogen Candida albicans via a multistep process which includes binding to Ssa1/2 proteins on the cell surface and requires the TRK1 potassium transporter. Hst 5-induced membrane permeability to propidium iodide (PI) was nearly abolished in strain CaTK1...

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Détails bibliographiques
Auteurs principaux: Vylkova, Slavena, Li, Xuewei S., Berner, Jennifer C., Edgerton, Mira
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2006
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1346820/
https://ncbi.nlm.nih.gov/pubmed/16377704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.1.324-331.2006
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