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Human β-Defensins Kill Candida albicans in an Energy-Dependent and Salt-Sensitive Manner without Causing Membrane Disruption

Human β-defensin 2 (hBD-2) and hBD-3 have potent fungicidal activity in the micromolar range. Although little is known about their mechanism of action against Candida species, some similarities to the antifungal mechanism of salivary peptide histatin 5 (Hst 5) seem to exist. Since hBD-2 and hBD-3 ha...

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Bibliographische Detailangaben
Hauptverfasser: Vylkova, Slavena, Nayyar, Namrata, Li, Wansheng, Edgerton, Mira
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797696/
https://ncbi.nlm.nih.gov/pubmed/17074797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00478-06
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