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Heterogeneous Macrolide Resistance and Gene Conversion in the Pneumococcus

A macrolide-resistant clinical isolate of Streptococcus pneumoniae with 23S rRNA mutations showed a heterogeneous phenotype and genotype. The mutant 23S rRNA genes from this isolate transformed susceptible strain R6 to resistance. Culture of resistant strain R6 in the absence of antibiotic pressure...

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Autors principals: Wolter, Nicole, Smith, Anthony M., Farrell, David J., Klugman, Keith P.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1346819/
https://ncbi.nlm.nih.gov/pubmed/16377711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.1.359-361.2006
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