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Lovastatin Has Significant Activity against Zygomycetes and Interacts Synergistically with Voriconazole

Zygomycetes are emerging opportunistic molds resistant to most conventional antifungals. We evaluated the in vitro activity of lovastatin (LOV), a 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor, against seven clinical isolates of Zygomycetes by using standard microdilution methods in thre...

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Bibliographische Detailangaben
Hauptverfasser: Chamilos, Georgios, Lewis, Russell E., Kontoyiannis, Dimitrios P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1346800/
https://ncbi.nlm.nih.gov/pubmed/16377673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.1.96-103.2006
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