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Biochemistry and Comparative Genomics of SxxK Superfamily Acyltransferases Offer a Clue to the Mycobacterial Paradox: Presence of Penicillin-Susceptible Target Proteins versus Lack of Efficiency of Penicillin as Therapeutic Agent

The bacterial acyltransferases of the SxxK superfamily vary enormously in sequence and function, with conservation of particular amino acid groups and all-α and α/β folds. They occur as independent entities (free-standing polypeptides) and as modules linked to other polypeptides (protein fusions). T...

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書誌詳細
出版年:Microbiol Mol Biol Rev
主要な著者: Goffin, Colette, Ghuysen, Jean-Marie
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 2002
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC134655/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12456788/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MMBR.66.4.702-738.2002
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