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Biochemistry and Comparative Genomics of SxxK Superfamily Acyltransferases Offer a Clue to the Mycobacterial Paradox: Presence of Penicillin-Susceptible Target Proteins versus Lack of Efficiency of Penicillin as Therapeutic Agent

The bacterial acyltransferases of the SxxK superfamily vary enormously in sequence and function, with conservation of particular amino acid groups and all-α and α/β folds. They occur as independent entities (free-standing polypeptides) and as modules linked to other polypeptides (protein fusions). T...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Microbiol Mol Biol Rev
Principais autores: Goffin, Colette, Ghuysen, Jean-Marie
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology (ASM) 2002
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC134655/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12456788/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MMBR.66.4.702-738.2002
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