Mice Deficient for the Wild-Type p53-Induced Phosphatase Gene (Wip1) Exhibit Defects in Reproductive Organs, Immune Function, and Cell Cycle Control

The Wip1 gene is a serine/threonine phosphatase that is induced in a p53-dependent manner by DNA-damaging agents. We show here that Wip1 message is expressed in moderate levels in all organs, but is present at very high levels in the testes, particularly in the postmeiotic round spermatid compartmen...

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Detalles Bibliográficos

Publicado en:	Mol Cell Biol
Autores principales:	Choi, Jene, Nannenga, Bonnie, Demidov, Oleg N., Bulavin, Dmitry V., Cooney, Austin, Brayton, Cory, Zhang, Yongxin, Mbawuike, Innocent N., Bradley, Allan, Appella, Ettore, Donehower, Lawrence A.
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Taylor & Francis 2002
Materias:	Mammalian Genetic Models with Minimal or Complex Phenotypes
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC134641/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11809801/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.4.1094-1105.2002
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