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Chk1 and p21 Cooperate to Prevent Apoptosis during DNA Replication Fork Stress
Cells respond to DNA replication stress by triggering cell cycle checkpoints, repair, or death. To understand the role of the DNA damage response pathways in determining whether cells survive replication stress or become committed to death, we examined the effect of loss of these pathways on cellula...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The American Society for Cell Biology
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1345677/ https://ncbi.nlm.nih.gov/pubmed/16280359 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E05-07-0594 |
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