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ATR-like kinase Mec1 facilitates both chromatin accessibility at DNA replication forks and replication fork progression during replication stress

Faithful DNA replication is essential for normal cell division and differentiation. In eukaryotic cells, DNA replication takes place on chromatin. This poses the critical question as to how DNA replication can progress through chromatin, which is inhibitory to all DNA-dependent processes. Here, we d...

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Detalhes bibliográficos
Main Authors: Rodriguez, Jairo, Tsukiyama, Toshio
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3553285/
https://ncbi.nlm.nih.gov/pubmed/23307868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.202978.112
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