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Removal of impurities from transcription factor preparations that alter their DNA-binding properties

Biochemical studies of transcriptional activators are important for understanding their detailed mechanism of action. Such experiments generally employ chimeric constructs comprised of fused DNA- binding and activation domains that are expressed in, and purified from, Escherichia coli, since full-le...

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Detalhes bibliográficos
Main Authors: Sun, Liping, Kodadek, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC134261/
https://ncbi.nlm.nih.gov/pubmed/12177316
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