Solid phase capturable dideoxynucleotides for multiplex genotyping using mass spectrometry

We report an approach using solid phase capturable biotinylated dideoxynucleotides (biotin-ddNTPs) in single base extension for multiplex genotyping by mass spectrometry (MS). In this method, oligonucleotide primers that have different molecular weights and that are specific to the polymorphic sites...

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Bibliographic Details
Main Authors: Kim, Sobin, Edwards, John R., Deng, Liyong, Chung, Wendy, Ju, Jingyue
Format: Artigo
Language:Inglês
Published: Oxford University Press 2002
Subjects:
NAR Methods Online
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC134258/
https://ncbi.nlm.nih.gov/pubmed/12177313
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