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Solid phase capturable dideoxynucleotides for multiplex genotyping using mass spectrometry

We report an approach using solid phase capturable biotinylated dideoxynucleotides (biotin-ddNTPs) in single base extension for multiplex genotyping by mass spectrometry (MS). In this method, oligonucleotide primers that have different molecular weights and that are specific to the polymorphic sites...

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Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Kim, Sobin, Edwards, John R., Deng, Liyong, Chung, Wendy, Ju, Jingyue
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2002
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC134258/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12177313/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gnf084
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