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Erk5 Participates in Neuregulin Signal Transduction and Is Constitutively Active in Breast Cancer Cells Overexpressing ErbB2

The four receptor tyrosine kinases of the ErbB family play essential roles in several physiological processes and have also been implicated in tumor generation and/or progression. Activation of ErbB1/EGFR is mainly triggered by epidermal growth factor (EGF) and other related ligands, while activatio...

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Autori principali: Esparís-Ogando, Azucena, Díaz-Rodríguez, Elena, Montero, Juan Carlos, Yuste, Laura, Crespo, Piero, Pandiella, Atanasio
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC134212/
https://ncbi.nlm.nih.gov/pubmed/11739740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.1.270-285.2002
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