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Identification of a Human Decapping Complex Associated with hUpf Proteins in Nonsense-Mediated Decay
Decapping is a key step in general and regulated mRNA decay. In Saccharomyces cerevisiae it constitutes a rate-limiting step in the nonsense-mediated decay pathway that rids cells of mRNAs containing premature termination codons. Here two human decapping enzymes are identified, hDcp1a and hDcp2, as...
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| Format: | Artigo |
| Jezik: | Inglês |
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American Society for Microbiology
2002
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| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC134073/ https://ncbi.nlm.nih.gov/pubmed/12417715 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.23.8114-8121.2002 |
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