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Identification of a Human Decapping Complex Associated with hUpf Proteins in Nonsense-Mediated Decay

Decapping is a key step in general and regulated mRNA decay. In Saccharomyces cerevisiae it constitutes a rate-limiting step in the nonsense-mediated decay pathway that rids cells of mRNAs containing premature termination codons. Here two human decapping enzymes are identified, hDcp1a and hDcp2, as...

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Autor principal: Lykke-Andersen, Jens
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC134073/
https://ncbi.nlm.nih.gov/pubmed/12417715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.23.8114-8121.2002
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