Transduction of Growth or Mitogenic Signals into Translational Activation of TOP mRNAs Is Fully Reliant on the Phosphatidylinositol 3-Kinase-Mediated Pathway but Requires neither S6K1 nor rpS6 Phosphorylation

Translation of terminal oligopyrimidine tract (TOP) mRNAs, which encode multiple components of the protein synthesis machinery, is known to be controlled by mitogenic stimuli. We now show that the ability of cells to progress through the cell cycle is not a prerequisite for this mode of regulation....

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Bibliografski detalji
Glavni autori: Stolovich, Miri, Tang, Hua, Hornstein, Eran, Levy, Galit, Cohen, Ruth, Bae, Sun Sik, Birnbaum, Morris J., Meyuhas, Oded
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2002
Teme:
Gene Expression
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC134064/
https://ncbi.nlm.nih.gov/pubmed/12417714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.23.8101-8113.2002
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