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The GCN2 eIF2α Kinase Is Required for Adaptation to Amino Acid Deprivation in Mice

The GCN2 eIF2α kinase is essential for activation of the general amino acid control pathway in yeast when one or more amino acids become limiting for growth. GCN2's function in mammals is unknown, but must differ, since mammals, unlike yeast, can synthesize only half of the standard 20 amino acids....

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Dades bibliogràfiques
Publicat a:Mol Cell Biol
Autors principals: Zhang, Peichuan, McGrath, Barbara C., Reinert, Jamie, Olsen, DeAnne S., Lei, Li, Gill, Sangeeta, Wek, Sheree A., Vattem, Krishna M., Wek, Ronald C., Kimball, Scot R., Jefferson, Leonard S., Cavener, Douglas R.
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2002
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC134046/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12215525/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.19.6681-6688.2002
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