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Isolation and Characterization of New Proliferating Cell Nuclear Antigen (POL30) Mutator Mutants That Are Defective in DNA Mismatch Repair

A number of studies have suggested a role for proliferating cell nuclear antigen (PCNA) in DNA mismatch repair (MMR). However, the majority of mutations in the POL30 gene encoding PCNA that cause MMR defects also cause replication and other repair defects that contribute to the increased mutation ra...

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Detalhes bibliográficos
Main Authors: Lau, Patrick J., Flores-Rozas, Hernan, Kolodner, Richard D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC134031/
https://ncbi.nlm.nih.gov/pubmed/12215524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.19.6669-6680.2002
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