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Novel Mechanism of Nuclear Receptor Corepressor Interaction Dictated by Activation Function 2 Helix Determinants

Transcriptional regulation by nuclear receptors is controlled by the concerted action of coactivator and corepressor proteins. The product of the thyroid hormone-regulated mammalian gene hairless (Hr) was recently shown to function as a thyroid hormone receptor corepressor. Here we report that Hr ac...

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Bibliografske podrobnosti
Main Authors: Moraitis, Anna N., Giguère, Vincent, Thompson, Catherine C.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2002
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC134023/
https://ncbi.nlm.nih.gov/pubmed/12215540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.19.6831-6841.2002
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