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Novel Mechanism of Nuclear Receptor Corepressor Interaction Dictated by Activation Function 2 Helix Determinants

Transcriptional regulation by nuclear receptors is controlled by the concerted action of coactivator and corepressor proteins. The product of the thyroid hormone-regulated mammalian gene hairless (Hr) was recently shown to function as a thyroid hormone receptor corepressor. Here we report that Hr ac...

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Detalhes bibliográficos
Main Authors: Moraitis, Anna N., Giguère, Vincent, Thompson, Catherine C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC134023/
https://ncbi.nlm.nih.gov/pubmed/12215540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.19.6831-6841.2002
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