C-Terminal Regions of the Human Telomerase Catalytic Subunit Essential for In Vivo Enzyme Activity

Most human cancer cells are thought to acquire the ability to divide beyond the capacity of normal somatic cells through illegitimately activating the gene hTERT, which encodes the catalytic subunit of telomerase. While telomerase reverse transcriptase (TERT) is conserved in most eukaryotes, mountin...

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Détails bibliographiques
Auteurs principaux: Banik, Soma S. R., Guo, Chuanhai, Smith, Allyson C., Margolis, Seth S., Richardson, D. Ashley, Tirado, Carlos A., Counter, Christopher M.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2002
Sujets:
DNA Dynamics and Chromosome Structure
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC134020/
https://ncbi.nlm.nih.gov/pubmed/12167716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.17.6234-6246.2002
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