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C-Terminal Regions of the Human Telomerase Catalytic Subunit Essential for In Vivo Enzyme Activity

Most human cancer cells are thought to acquire the ability to divide beyond the capacity of normal somatic cells through illegitimately activating the gene hTERT, which encodes the catalytic subunit of telomerase. While telomerase reverse transcriptase (TERT) is conserved in most eukaryotes, mountin...

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Bibliografische Detailangaben
Veröffentlicht in:Mol Cell Biol
Hauptverfasser: Banik, Soma S. R., Guo, Chuanhai, Smith, Allyson C., Margolis, Seth S., Richardson, D. Ashley, Tirado, Carlos A., Counter, Christopher M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2002
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC134020/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12167716/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.17.6234-6246.2002
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