C-Terminal Regions of the Human Telomerase Catalytic Subunit Essential for In Vivo Enzyme Activity

Most human cancer cells are thought to acquire the ability to divide beyond the capacity of normal somatic cells through illegitimately activating the gene hTERT, which encodes the catalytic subunit of telomerase. While telomerase reverse transcriptase (TERT) is conserved in most eukaryotes, mountin...

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Главные авторы: Banik, Soma S. R., Guo, Chuanhai, Smith, Allyson C., Margolis, Seth S., Richardson, D. Ashley, Tirado, Carlos A., Counter, Christopher M.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2002
Предметы:
DNA Dynamics and Chromosome Structure
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC134020/
https://ncbi.nlm.nih.gov/pubmed/12167716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.17.6234-6246.2002
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