C-Terminal Regions of the Human Telomerase Catalytic Subunit Essential for In Vivo Enzyme Activity

Most human cancer cells are thought to acquire the ability to divide beyond the capacity of normal somatic cells through illegitimately activating the gene hTERT, which encodes the catalytic subunit of telomerase. While telomerase reverse transcriptase (TERT) is conserved in most eukaryotes, mountin...

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Detalhes bibliográficos
Main Authors: Banik, Soma S. R., Guo, Chuanhai, Smith, Allyson C., Margolis, Seth S., Richardson, D. Ashley, Tirado, Carlos A., Counter, Christopher M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
DNA Dynamics and Chromosome Structure
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC134020/
https://ncbi.nlm.nih.gov/pubmed/12167716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.17.6234-6246.2002
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