High Bone Resorption in Adult Aging Transgenic Mice Overexpressing Cbfa1/Runx2 in Cells of the Osteoblastic Lineage

The runt family transcription factor core-binding factor α1 (Cbfa1) is essential for bone formation during development. Surprisingly, transgenic mice overexpressing Cbfa1 under the control of the 2.3-kb collagen type I promoter developed severe osteopenia that increased progressively with age and pr...

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書誌詳細

出版年:	Mol Cell Biol
主要な著者:	Geoffroy, Valérie, Kneissel, Michaela, Fournier, Brigitte, Boyde, Alan, Matthias, Patrick
フォーマット:	Artigo
言語:	Inglês
出版事項:	Taylor & Francis 2002
主題:	Cell Growth and Development
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC134019/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12167715/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.17.6222-6233.2002
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