High Bone Resorption in Adult Aging Transgenic Mice Overexpressing Cbfa1/Runx2 in Cells of the Osteoblastic Lineage
The runt family transcription factor core-binding factor α1 (Cbfa1) is essential for bone formation during development. Surprisingly, transgenic mice overexpressing Cbfa1 under the control of the 2.3-kb collagen type I promoter developed severe osteopenia that increased progressively with age and pr...
Bewaard in:
| Gepubliceerd in: | Mol Cell Biol |
|---|---|
| Hoofdauteurs: | , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Taylor & Francis
2002
|
| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC134019/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12167715/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.17.6222-6233.2002 |
| Tags: |
Geen labels, Wees de eerste die dit record labelt!
|