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Regulation of α-Fetoprotein Expression by Nkx2.8

The α-fetoprotein (AFP) gene is an important model of developmental gene silencing and neoplastic gene reactivation. Nkx2.8 is a divergent homeodomain factor originally cloned through its binding to the promoter-coupling element (PCE), a regulatory region upstream of the AFP promoter that mediates s...

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Detalhes bibliográficos
Main Authors: Kajiyama, Yasuo, Tian, Jianmin, Locker, Joseph
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC134004/
https://ncbi.nlm.nih.gov/pubmed/12167706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.17.6122-6130.2002
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