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Regulation of α-Fetoprotein Expression by Nkx2.8
The α-fetoprotein (AFP) gene is an important model of developmental gene silencing and neoplastic gene reactivation. Nkx2.8 is a divergent homeodomain factor originally cloned through its binding to the promoter-coupling element (PCE), a regulatory region upstream of the AFP promoter that mediates s...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology
2002
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC134004/ https://ncbi.nlm.nih.gov/pubmed/12167706 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.17.6122-6130.2002 |
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