c-Myc Functionally Cooperates with Bax To Induce Apoptosis
c-Myc promotes apoptosis by destabilizing mitochondrial integrity, leading to the release of proapoptotic effectors including holocytochrome c. Candidate mediators of c-Myc in this process are the proapoptotic members of the Bcl-2 family. We show here that fibroblasts lacking Bak remain susceptible...
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| Gepubliceerd in: | Mol Cell Biol |
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| Hoofdauteurs: | , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Taylor & Francis
2002
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC133996/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12167710/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.17.6158-6169.2002 |
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