The Bax Subfamily of Bcl2-Related Proteins Is Essential for Apoptotic Signal Transduction by c-Jun NH(2)-Terminal Kinase

Targeted gene disruption studies have established that the c-Jun NH(2)-terminal kinase (JNK) signaling pathway is required for stress-induced release of mitochondrial cytochrome c and apoptosis. Here we demonstrate that activated JNK is sufficient to induce rapid cytochrome c release and apoptosis....

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Lei, Kui, Nimnual, Anjaruwee, Zong, Wei-Xing, Kennedy, Norman J., Flavell, Richard A., Thompson, Craig B., Bar-Sagi, Dafna, Davis, Roger J.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2002
Assuntos:	Cell Growth and Development
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC133923/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12052897/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.13.4929-4942.2002
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