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Regulation of c-myc mRNA Decay by Translational Pausing in a Coding Region Instability Determinant
A 249-nucleotide coding region instability determinant (CRD) destabilizes c-myc mRNA. Previous experiments identified a CRD-binding protein (CRD-BP) that appears to protect the CRD from endonuclease cleavage. However, it was unclear why a CRD-BP is required to protect a well-translated mRNA whose co...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2002
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC133878/ https://ncbi.nlm.nih.gov/pubmed/12024010 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.12.3959-3969.2002 |
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