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Antagonistic Interactions between Yeast [PSI(+)] and [URE3] Prions and Curing of [URE3] by Hsp70 Protein Chaperone Ssa1p but Not by Ssa2p

The yeast [PSI(+)], [URE3], and [PIN(+)] genetic elements are prion forms of Sup35p, Ure2p, and Rnq1p, respectively. Overexpression of Sup35p, Ure2p, or Rnq1p leads to increased de novo appearance of [PSI(+)], [URE3], and [PIN(+)], respectively. This inducible appearance of [PSI(+)] was shown to be...

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Bibliographic Details
Main Authors: Schwimmer, Christine, Masison, Daniel C.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2002
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC133818/
https://ncbi.nlm.nih.gov/pubmed/11997496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.11.3590-3598.2002
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