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Single methyl group determines prion propagation and protein degradation activities of yeast heat shock protein (Hsp)-70 chaperones Ssa1p and Ssa2p

Organisms encode multiple homologous heat shock protein (Hsp)-70s, which are essential protein chaperones that play the major role in cellular protein “quality control.” Although Hsp70s are functionally redundant and highly homologous, many possess distinct functions. A regulatory motif underlying s...

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Detalles Bibliográficos
Main Authors: Sharma, Deepak, Masison, Daniel C.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3158190/
https://ncbi.nlm.nih.gov/pubmed/21808014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1107421108
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