p53 Binds and Activates the Xeroderma Pigmentosum DDB2 Gene in Humans but Not Mice

The DDB2 gene, which is mutated in xeroderma pigmentosum group E, enhances global genomic repair of cyclobutane pyrimidine dimers and suppresses UV-induced mutagenesis. Because DDB2 transcription increases after DNA damage in a p53-dependent manner, we searched for and found a region in the human DD...

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Bibliografische gegevens

Gepubliceerd in:	Mol Cell Biol
Hoofdauteurs:	Tan, Thomas, Chu, Gilbert
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Taylor & Francis 2002
Onderwerpen:	Transcriptional Regulation
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC133779/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11971958/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.10.3247-3254.2002
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