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p53 Is Necessary for the Apoptotic Response Mediated by a Transient Increase of Ras Activity
The tumor suppressor p53 eliminates cancer-prone cells via multiple mechanisms, including apoptosis. Ras elicits apoptosis in cells after protein kinase C (PKC) downregulation. However, the role of p53 in Ras-mediated apoptosis has not been fully investigated. Here, we demonstrate that mouse fibrobl...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology
2002
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC133752/ https://ncbi.nlm.nih.gov/pubmed/11940651 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.9.2928-2938.2002 |
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