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Tumor Necrosis Factor Receptor 1 Is an ATPase Regulated by Silencer of Death Domain

Self-aggregation of tumor necrosis factor receptor type 1 (TNFR1) induces spontaneous downstream signaling and results in cell death. It has been suggested that silencer of death domain (SODD) binds TNFR1 monomers to prevent self-aggregation. We found that SODD binds through its BAG domain to the AT...

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Bibliographic Details
Main Authors: Miki, Kiyoshi, Eddy, Edward M.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2002
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC133739/
https://ncbi.nlm.nih.gov/pubmed/11909948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.8.2536-2543.2002
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