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Tumor Necrosis Factor Receptor 1 Is an ATPase Regulated by Silencer of Death Domain
Self-aggregation of tumor necrosis factor receptor type 1 (TNFR1) induces spontaneous downstream signaling and results in cell death. It has been suggested that silencer of death domain (SODD) binds TNFR1 monomers to prevent self-aggregation. We found that SODD binds through its BAG domain to the AT...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Microbiology
2002
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC133739/ https://ncbi.nlm.nih.gov/pubmed/11909948 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.8.2536-2543.2002 |
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