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Scatter Factor/Hepatocyte Growth Factor Stimulation of Glioblastoma Cell Cycle Progression through G(1) Is c-Myc Dependent and Independent of p27 Suppression, Cdk2 Activation, or E2F1-Dependent Transcription

Scatter factor/hepatocyte growth factor (SF/HGF) expression has been linked to malignant progression in glial neoplasms. Using two glioma cell lines, U373MG and SNB-19, we have demonstrated that SF/HGF stimulation allows cells to escape G(1)/G(0) arrest induced by contact inhibition or serum withdra...

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Bibliographic Details
Main Authors: Walter, Kevin A., Hossain, Mir Ahamed, Luddy, Carey, Goel, Nidhi, Reznik, Thomas E., Laterra, John
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2002
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC133707/
https://ncbi.nlm.nih.gov/pubmed/11909963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.8.2703-2715.2002
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