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The Two ADF-H Domains of Twinfilin Play Functionally Distinct Roles in Interactions with Actin Monomers
Twinfilin is a ubiquitous and abundant actin monomer–binding protein that is composed of two ADF-H domains. To elucidate the role of twinfilin in actin dynamics, we examined the interactions of mouse twinfilin and its isolated ADF-H domains with G-actin. Wild-type twinfilin binds ADP-G-actin with hi...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The American Society for Cell Biology
2002
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC133594/ https://ncbi.nlm.nih.gov/pubmed/12429826 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E02-03-0157 |
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