NUP98–HOXA9 expression in hemopoietic stem cells induces chronic and acute myeloid leukemias in mice

Here we describe hemopoietic chimeras serving as a mouse model for NUP98–HOXA9-induced leukemia, which reproduced several of the phenotypes observed in human disease. Mice transplanted with bone marrow cells expressing NUP98–HOXA9 through retroviral transduction acquire a myeloproliferative disease...

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Bibliografische gegevens

Gepubliceerd in:	EMBO J
Hoofdauteurs:	Kroon, Evert, Thorsteinsdottir, Unnur, Mayotte, Nadine, Nakamura, Takuro, Sauvageau, Guy
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Nature Publishing Group 2001
Onderwerpen:	Article
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC133485/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11157742/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.3.350
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