NUP98–HOXA9 expression in hemopoietic stem cells induces chronic and acute myeloid leukemias in mice
Here we describe hemopoietic chimeras serving as a mouse model for NUP98–HOXA9-induced leukemia, which reproduced several of the phenotypes observed in human disease. Mice transplanted with bone marrow cells expressing NUP98–HOXA9 through retroviral transduction acquire a myeloproliferative disease...
में बचाया:
| में प्रकाशित: | EMBO J |
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| मुख्य लेखकों: | , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Nature Publishing Group
2001
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC133485/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11157742/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.3.350 |
| टैग: |
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