Stat5a/b are essential for normal lymphoid development and differentiation

Cytokines that use the common gamma chain γc are critical for lymphoid development and function. Mutations of the IL-7 receptor, γc, or its associated kinase, Jak3, are the major cause of human severe combined immunodeficiency. Although activated by IL-7, Stat5a/b (Stat, signal transducer and activa...

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Detalles Bibliográficos
Main Authors: Yao, Zhengju, Cui, Yongzhi, Watford, Wendy T., Bream, Jay H., Yamaoka, Kunihiro, Hissong, Bruce D., Li, Denise, Durum, Scott K., Jiang, Qiong, Bhandoola, Avinash, Hennighausen, Lothar, O'Shea, John J.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2006
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1327727/
https://ncbi.nlm.nih.gov/pubmed/16418296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0507350103
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