Antiviral Activities and Cellular Toxicities of Modified 2′,3′-Dideoxy-2′,3′-Didehydrocytidine Analogues

The antiviral efficacies and cytotoxicities of 2′,3′- and 4′-substituted 2′,3′-didehydro-2′,3′-dideoxycytidine analogs were evaluated. All compounds were tested (i) against a wild-type human immunodeficiency virus type 1 (HIV-1) isolate (strain xxBRU) and lamivudine-resistant HIV-1 isolates, (ii) fo...

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發表在:	Antimicrob Agents Chemother
Principais autores:	Stuyver, Lieven J., Lostia, Stefania, Adams, Marjorie, Mathew, Judy S., Pai, Balakrishna S., Grier, Jason, Tharnish, Phillip M., Choi, Yongseok, Chong, Youhoon, Choo, Hyunah, Chu, Chung K., Otto, Michael J., Schinazi, Raymond F.
格式:	Artigo
語言:	Inglês
出版:	American Society for Microbiology (ASM) 2002
主題:	Antiviral Agents
在線閱讀:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC132758/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12435688/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.12.3854-3860.2002
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