Antiviral Activities and Cellular Toxicities of Modified 2′,3′-Dideoxy-2′,3′-Didehydrocytidine Analogues

The antiviral efficacies and cytotoxicities of 2′,3′- and 4′-substituted 2′,3′-didehydro-2′,3′-dideoxycytidine analogs were evaluated. All compounds were tested (i) against a wild-type human immunodeficiency virus type 1 (HIV-1) isolate (strain xxBRU) and lamivudine-resistant HIV-1 isolates, (ii) fo...

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Detaylı Bibliyografya
Asıl Yazarlar: Stuyver, Lieven J., Lostia, Stefania, Adams, Marjorie, Mathew, Judy S., Pai, Balakrishna S., Grier, Jason, Tharnish, Phillip M., Choi, Yongseok, Chong, Youhoon, Choo, Hyunah, Chu, Chung K., Otto, Michael J., Schinazi, Raymond F.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2002
Konular:
Antiviral Agents
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC132758/
https://ncbi.nlm.nih.gov/pubmed/12435688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.12.3854-3860.2002
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