Antiviral Activities and Cellular Toxicities of Modified 2′,3′-Dideoxy-2′,3′-Didehydrocytidine Analogues

The antiviral efficacies and cytotoxicities of 2′,3′- and 4′-substituted 2′,3′-didehydro-2′,3′-dideoxycytidine analogs were evaluated. All compounds were tested (i) against a wild-type human immunodeficiency virus type 1 (HIV-1) isolate (strain xxBRU) and lamivudine-resistant HIV-1 isolates, (ii) fo...

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Hlavní autoři: Stuyver, Lieven J., Lostia, Stefania, Adams, Marjorie, Mathew, Judy S., Pai, Balakrishna S., Grier, Jason, Tharnish, Phillip M., Choi, Yongseok, Chong, Youhoon, Choo, Hyunah, Chu, Chung K., Otto, Michael J., Schinazi, Raymond F.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2002
Témata:
Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC132758/
https://ncbi.nlm.nih.gov/pubmed/12435688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.12.3854-3860.2002
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