Intramuscular Bioavailability and Clinical Efficacy of Artesunate in Gabonese Children with Severe Malaria

Artesunate (ARS) is a water-soluble artemisinin derivative that is a potential alternative to quinine for the treatment of severe childhood malaria. We studied the pharmacokinetics and bioavailability of ARS given by the intramuscular (i.m.) route in an open crossover study design. Fourteen children...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Nealon, Claire, Dzeing, Arnaud, Müller-Römer, Ulrich, Planche, Timothy, Sinou, Veronique, Kombila, Maryvonne, Kremsner, Peter G., Parzy, Daniel, Krishna, Sanjeev
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2002
Assuntos:	Pharmacology
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC132755/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12435698/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.12.3933-3939.2002
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