Intramuscular Bioavailability and Clinical Efficacy of Artesunate in Gabonese Children with Severe Malaria

Artesunate (ARS) is a water-soluble artemisinin derivative that is a potential alternative to quinine for the treatment of severe childhood malaria. We studied the pharmacokinetics and bioavailability of ARS given by the intramuscular (i.m.) route in an open crossover study design. Fourteen children...

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Publié dans:	Antimicrob Agents Chemother
Auteurs principaux:	Nealon, Claire, Dzeing, Arnaud, Müller-Römer, Ulrich, Planche, Timothy, Sinou, Veronique, Kombila, Maryvonne, Kremsner, Peter G., Parzy, Daniel, Krishna, Sanjeev
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 2002
Sujets:	Pharmacology
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC132755/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12435698/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.12.3933-3939.2002
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