Intramuscular Bioavailability and Clinical Efficacy of Artesunate in Gabonese Children with Severe Malaria

Artesunate (ARS) is a water-soluble artemisinin derivative that is a potential alternative to quinine for the treatment of severe childhood malaria. We studied the pharmacokinetics and bioavailability of ARS given by the intramuscular (i.m.) route in an open crossover study design. Fourteen children...

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Bibliographische Detailangaben
Hauptverfasser: Nealon, Claire, Dzeing, Arnaud, Müller-Römer, Ulrich, Planche, Timothy, Sinou, Veronique, Kombila, Maryvonne, Kremsner, Peter G., Parzy, Daniel, Krishna, Sanjeev
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2002
Schlagworte:
Pharmacology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC132755/
https://ncbi.nlm.nih.gov/pubmed/12435698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.12.3933-3939.2002
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