Effect of Auristatin PHE on Microtubule Integrity and Nuclear Localization in Cryptococcus neoformans

The mechanism of action of the fungicidal peptide auristatin PHE was investigated in Cryptococcus neoformans. Since auristatin PHE causes budding arrest in C. neoformans (T. Woyke, G. R. Pettit, G. Winkelmann, and R. K. Pettit, Antimicrob. Agents Chemother. 45:3580-3584, 2001), microtubule integrity...

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Detalles Bibliográficos

Publicado en:	Antimicrob Agents Chemother
Autores principales:	Woyke, Tanja, Roberson, Robert W., Pettit, George R., Winkelmann, Günther, Pettit, Robin K.
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 2002
Materias:	Mechanisms of Action: Physiological Effects
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC132747/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12435680/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.12.3802-3808.2002
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