Effect of Auristatin PHE on Microtubule Integrity and Nuclear Localization in Cryptococcus neoformans

The mechanism of action of the fungicidal peptide auristatin PHE was investigated in Cryptococcus neoformans. Since auristatin PHE causes budding arrest in C. neoformans (T. Woyke, G. R. Pettit, G. Winkelmann, and R. K. Pettit, Antimicrob. Agents Chemother. 45:3580-3584, 2001), microtubule integrity...

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Detalhes bibliográficos
Main Authors: Woyke, Tanja, Roberson, Robert W., Pettit, George R., Winkelmann, Günther, Pettit, Robin K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Mechanisms of Action: Physiological Effects
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC132747/
https://ncbi.nlm.nih.gov/pubmed/12435680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.12.3802-3808.2002
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