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Specific Activities of Dolastatin 10 and Peptide Derivatives against Cryptococcus neoformans

The biosynthetic peptide dolastatin 10 is currently in phase I and II cancer clinical trials. We evaluated the antifungal spectrum of dolastatin 10 and four structural modifications. In broth macrodilution assays, the peptides were fungicidal for American Type Culture Collection strains and clinical...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Pettit, Robin K., Pettit, George R., Hazen, Kevin C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 1998
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC105973/
https://ncbi.nlm.nih.gov/pubmed/9797233
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