Specific Activities of Dolastatin 10 and Peptide Derivatives against Cryptococcus neoformans

The biosynthetic peptide dolastatin 10 is currently in phase I and II cancer clinical trials. We evaluated the antifungal spectrum of dolastatin 10 and four structural modifications. In broth macrodilution assays, the peptides were fungicidal for American Type Culture Collection strains and clinical...

Full beskrivning

Bibliografiska uppgifter

I publikationen:	Antimicrob Agents Chemother
Huvudupphov:	Pettit, Robin K., Pettit, George R., Hazen, Kevin C.
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	American Society for Microbiology (ASM) 1998
Ämnen:	Susceptibility
Länkar:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105973/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9797233/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.11.2961
Taggar:	Lägg till en tagg Inga taggar, Lägg till första taggen!